Diindolylmethane (DIM)

Diindolylmethane (DIM)
Image of Diindolylmethane (DIM) | C17H14N2 | Supreme Pharmavet
Chemical FormulaC17H14N2
Molecular weight246.313 g/mol
Names and Identifiers
PubChem Link
Traditional NameDiindolylmethane (DIM), 3,3′-Diindolylmethane
CAS Registry Number1968-05-4


3,3′-Diindolylmethane (DIM) is a compound derived from the digestion of indole-3-carbinol, found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage and kale. The reputation of Brassica vegetables as healthy foods rests in part on the activities of diindolylmethane.

Clinical data for the effects of DIM are limited, but because of potential anticancer properties, the National Cancer Institute of the United States has begun clinical trials of DIM as a therapeutic for numerous forms of cancer. Much of the scientific interest is due to its action as a histone deacetylase inhibitor in vitro, specifically against HDAC1, HDAC2, and HDAC3.

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