Collagen type-II

Collagen type-II
Image of Collagen type-II | C106H174N32O37 | Supreme Pharmavet
Chemical FormulaC106H174N32O37
Molecular weight2488.745 g/mol
Names and Identifiers
PubChem Link
Traditional NameType II collagen
CAS Registry Number144703-90-2


Type II collagen is the basis for articular cartilage and hyaline cartilage, formed by homotrimers of collagen, type II, alpha 1 chains.

It makes up 50% of all protein in cartilage and 85–90% of collagen of articular cartilage.

Type II collagen does form fibrils. This fibrillar network of collagen allows cartilage to entrap the proteoglycan aggregate as well as provide tensile strength to the tissue. Oral administration of native type II collagen induces oral tolerance to pathological immune responses and may be useful in arthritis.

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